Search DIAN Tissue Requests

In order to avoid the situation where two investigators study the same research question, please search our database to determine if your topic has already been studied. If you find that your topic or a related topic has already been submitted, you may wish to contact the investigator to inquire about his/her findings to determine how you might proceed. You may wish to collaborate or modify your request to avoid overlap. The results below reflect requests made since online requests have been accepted. As such, not all fields will have data as certain information, such as aims, were not collected until recently. If an entry has been assigned an ID # (e.g. DIAN-T1004), the full request has been submitted and is either approved, disapproved or in process.

Displaying 61 - 62 of 62

Investigator:

Jacques P. Tremblay

Title:

Development of a treatment of Alzheimer based on the editing of the Amyloid Precuror Protein gene with the CRISPR system

Date of Request:

10/24/2016

ID:

DIAN-T1613

Aim 1:

To correct the APP gene in 293T cells and in Alzheimer cells with a pair of gRNA (targeting sequences in intron 15 or 16) and with dCas9-FokI

Investigator:

Young-Pearse

Title:

Investigating Cell-type dependent phenotypes in familial Alzheimer's disease

Date of Request:

12/27/2016

ID:

DIAN-T1701

Aim 1:

To determine if there are differential effects of neuronal subtype on APP processing with fAD mutation

Aim 2:

To determine if there are differential effects of neuronal subtype on tau proteostasis with fAD mutation