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Dominantly Inherited Alzheimer Network (DIAN)

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Category: DIAN Scientific Advancements

Researchers find a hint at how to delay Alzheimer’s symptoms. Now they have to prove it (Links to an external site)

March 20, 2025March 21, 2025

Small study hints anti-amyloid therapy may keep Alzheimer’s symptoms at bay in certain patients (Links to an external site)

March 20, 2025March 21, 2025

For the first time, scientists say, they have evidence that using a biologic drug to remove sticky beta amyloid plaques from the brains of people destined to develop Alzheimer’s dementia can delay the disease.

Anti-amyloid drug shows signs of preventing Alzheimer’s dementia (Links to an external site)

March 20, 2025March 21, 2025

Clinical trial of people destined to develop early-onset Alzheimer’s disease shows eliminating amyloid from brain may prevent symptoms, supports need for confirmatory studies

Scientists Announce Possible Breakthrough in Delaying Alzheimer’s (Links to an external site)

March 19, 2025March 21, 2025

Research announced today is the first of its kind to suggest that anti-amyloid drugs can delay or even stop the progression of symptoms in people with early-onset Alzheimer’s.

First Success Stories From Alzheimer’s Secondary Prevention Trial (Links to an external site)

August 13, 2024December 13, 2024

As discussed at the Alzheimer’s Association International Conference in Philadelphia, nearly two dozen mutation carriers who took gantenerumab for eight years had half the risk of developing symptoms as did untreated controls.

Living Among Us: People Whose Alzheimer’s Is Already Being Prevented (Links to an external site)

August 9, 2024December 13, 2024

Many researchers think the full promise of plaque removal lies in prevention. If plaques were abolished before they could kick off downstream pathologies such as tangles, would the disease be stopped in its tracks?

The New Age of Alzheimer’s (Links to an external site)

April 18, 2024October 7, 2024

The soaring burden of dementia threatens global health. Science is paving new paths to solutions.

First Subject Enrolled in Phase II/III Study of Eisai’s Anti-MTBR Tau Antibody E2814 for Dominantly Inherited Alzheimer’s Disease (DIAD), conducted by DIAN-TU (Links to an external site)

January 19, 2022January 21, 2022

In DIAN-TU, Gantenerumab Brings Down Tau. By a Lot. Open Extension Planned (Links to an external site)

April 13, 2020April 13, 2020

Confused About the DIAN-TU Trial Data? Experts Discuss Nuances (Links to an external site)

April 13, 2020April 13, 2020

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