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Dominantly Inherited Alzheimer Network (DIAN)

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Participant Articles: Non-WashU

He Was Expected to Get Alzheimer’s 25 Years Ago. Why Hasn’t He? (Links to an external site)

The New York Times October 7, 2025
He Was Expected to Get Alzheimer’s 25 Years Ago. Why Hasn’t He?
Scientists are searching for the secret in Doug Whitney’s biology that has protected him from dementia, hoping it could lead to ways to treat or prevent Alzheimer’s for many other people.

Three Siblings, One Fatal Gene: A Family’s Fight Against Early-Onset Alzheimer’s (Links to an external site)

The Wall Street Journal June 28, 2025
Three Siblings, One Fatal Gene: A Family’s Fight Against Early-Onset Alzheimer’s
Among members of the Richardson family who carry a mutation in the PSEN1 gene, the average age when symptoms start is 39

Uncertainty around NIH funding leaves Alzheimer’s studies in limbo (Links to an external site)

CNN April 24, 2025
Uncertainty around NIH funding leaves Alzheimer’s studies in limbo

Researchers find a hint at how to delay Alzheimer’s symptoms. Now they have to prove it (Links to an external site)

AP March 20, 2025
Researchers find a hint at how to delay Alzheimer’s symptoms. Now they have to prove it

Small study hints anti-amyloid therapy may keep Alzheimer’s symptoms at bay in certain patients (Links to an external site)

CNN March 20, 2025
Small study hints anti-amyloid therapy may keep Alzheimer’s symptoms at bay in certain patients
For the first time, scientists say, they have evidence that using a biologic drug to remove sticky beta amyloid plaques from the brains of people destined to develop Alzheimer’s dementia can delay the disease.

Anti-amyloid drug shows signs of preventing Alzheimer’s dementia (Links to an external site)

WashU Medicine News Release March 20, 2025
Anti-amyloid drug shows signs of preventing Alzheimer’s dementia
Clinical trial of people destined to develop early-onset Alzheimer’s disease shows eliminating amyloid from brain may prevent symptoms, supports need for confirmatory studies

His genes forecast Alzheimer’s. His brain had other plans. (Links to an external site)

NPR February 12, 2025
His genes forecast Alzheimer’s. His brain had other plans.

Conquering Alzheimer’s: a look at the therapies of the future (Links to an external site)

Nature – Apr 4, 2023 April 7, 2023
Conquering Alzheimer’s: a look at the therapies of the future

Seeking Alzheimer’s clues from few who escape genetic fate (Links to an external site)

AP News – March 16, 2023 March 20, 2023
Seeking Alzheimer’s clues from few who escape genetic fate

Could drugs prevent Alzheimer’s? These trials aim to find out (Links to an external site)

Nature – Mar 9, 2022 March 9, 2022
Could drugs prevent Alzheimer’s? These trials aim to find out

The Search for a Drug to End Alzheimer’s (Links to an external site)

IEEE Pulse June 3, 2021
The Search for a Drug to End Alzheimer’s
Some antiamyloids remove target plaques from the brain, yet don’t seem to halt cognitive decline. Researchers are working to understand why.

Aiming at the Tangle’s Heart? DIAN-TU Trial to Torpedo Tau’s Core (Links to an external site)

ALZFORUM – MAR 18, 2021 March 18, 2021

Encouraging findings in Alzheimer’s prevention trial lead to the next phase (Links to an external site)

Neuroscience Research Australia (NeuRA) website – MAR 15, 2021 March 16, 2021

AAIC 2020, dallo studio DIAN-TU la terapia contro l’Alzheimer (Links to an external site)

affaritaliani.it, 31 luglio 2020 July 31, 2020
AAIC 2020, dallo studio DIAN-TU la terapia contro l’Alzheimer

Elixir Factor Podcast S2 Ep6: Dominantly Inherited Alzheimer’s Disease: A View From Within (Links to an external site)

Lilly July 28, 2020
Elixir Factor Podcast S2 Ep6: Dominantly Inherited Alzheimer’s Disease: A View From Within

In DIAN-TU, Gantenerumab Brings Down Tau. By a Lot. Open Extension Planned (Links to an external site)

Alzforum – Apr 10, 2020 April 13, 2020

Confused About the DIAN-TU Trial Data? Experts Discuss Nuances (Links to an external site)

Alzforum – Apr 10, 2020 April 13, 2020

DIAN-TU Mcdade: “Nel 2020 sapremo se possiamo bloccare l’Alzheimer” (Links to an external site)

affaritaliani.it, 23 dicembre 2019 December 23, 2019
DIAN-TU Mcdade: “Nel 2020 sapremo se possiamo bloccare l’Alzheimer”

Wash U leading worldwide Alzheimer’s study (Links to an external site)

KSDK – ST. LOUIS LOCAL NEWS, OCTOBER 15, 2019 October 17, 2019
Wash U leading worldwide Alzheimer’s study

2019 DIAD Family Conference: Mutation, Participation, Innovation (Links to an external site)

Alzforum, August 2, 2019 August 9, 2019

The heartbreak and heroism of being the X-Men in Alzheimer’s disease (Links to an external site)

St. Louis Post-Dispatch, February 10, 2019 February 11, 2019
The heartbreak and heroism of being the X-Men in Alzheimer’s disease

‘Everything is for Alexis’: She is not yet 2. Her father fears she will have Alzheimer’s. (Links to an external site)

The Washington Post, December 8, 2018 December 12, 2018
‘Everything is for Alexis’: She is not yet 2. Her father fears she will have Alzheimer’s.
Andres Martin, a 31-year-old Marine, is being treated at Walter Reed National Military Medical Center for a rare form of Alzheimer’s disease that impacts people with roots in Jalisco, Mexico. He worries his daughter, Alexis, who is not yet 2, will also have it.

Early Clues (Links to an external site)

Brain & Life, American Academy of Neurology, October/November 2018 October 12, 2018

Rara mutación genética provoca enfermedad en personas jóvenes (Links to an external site)

Telemundo, 6 de febrero, 2018 February 7, 2018
Rara mutación genética provoca enfermedad en personas jóvenes

Dementia and us: portraits of heartbreak and hope (Links to an external site)

Financial Times, December 2017 December 22, 2017
Dementia and us: portraits of heartbreak and hope

6 Siblings Living In The Shadow Of Alzheimer’s (Links to an external site)

Today, March 30, 2017 November 13, 2017
6 Siblings Living In The Shadow Of Alzheimer’s

Alzheimer’s-Every Minute Counts (Links to an external site)

PBS – January 2017 January 25, 2017
Alzheimer’s-Every Minute Counts

Alzheimer’s Disease: Daisy’s Story (Links to an external site)

HECTV – March 2016 April 5, 2016

34-year-old woman travels to Wash U for Alzheimer’s trial (Links to an external site)

KSDK – November 2015 November 5, 2015
34-year-old woman travels to Wash U for Alzheimer’s trial
A devastating disease that can rob you of your memory has an Alabama woman traveling to Missouri for help. The mother of three is taking part in a ground breaking study led by Washington University. Carrie Richardson, a 34-year-old preschool teacher and mother of three is in the fight of her life.

Alzheimer’s: New clues in search for cure (Links to an external site)

CBS News – October 2011 October 5, 2011
Alzheimer’s: New clues in search for cure
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