A changing landscape: Alzheimer’s disease, research and the future of care (Links to an external site)
Ongoing international research led by Washington University investigators is changing the Alzheimer’s disease landscape from hopeless to hopeful.
Eli Lilly’s Experimental Alzheimer’s Drug Fails in Large Trial (Links to an external site)
An experimental Alzheimer’s drug that had previously appeared to show promise in slowing the deterioration of thinking and memory has failed in a large Eli Lilly clinical trial, dealing a significant disappointment to patients hoping for a treatment that would alleviate their symptoms.
Dominantly Inherited Alzheimer Network Trial (DIAN-TU-001) continues despite results from Eli Lilly and Company’s EXPEDITION3 trial (Links to an external site)
German Families with Dominantly Inherited Alzheimer’s Disease Meet for the First Time (Links to an external site)
Nobody knew each other’s name. Even so, 60 people who either were at risk of having an autosomal-dominant Alzheimer’s mutation, or were accompanying someone who was, exchanged information about a shared problem. There were moments of validation—“Denial has divided my family, too!”—and apprehensive questions—“Do you want to know if you have it?”
Why Most Alzheimer’s Research Is Done On Early-Onset Patients Like Pat Summitt (Links to an external site)
$4 million grant expands major study to find Alzheimer’s prevention treatments (Links to an external site)
Washington University School of Medicine in St. Louis has received a $4.3 million award from the Alzheimer’s Association to expand a major international clinical trial evaluating whether drugs can prevent Alzheimer’s disease in patients genetically predisposed to develop the devastating disease at a young age.
Family places hope in drug trial for hereditary Alzheimer’s gene mutation (Links to an external site)
Alzheimer’s Disease: Daisy’s Story (Links to an external site)
Man looking for answers with new Alzheimer’s study (Links to an external site)
He has the disease and he’s lost five family members to it, now he’s enrolled in a study hoping to find some answers in Alzheimer’s disease.
Trial aims to prevent Alzheimer’s in those genetically predisposed (Links to an external site)
A first-of-its-kind study is testing the use of antibody drugs to prevent or slow down the onset of Alzheimer’s disease in individuals genetically destined to develop the illness at an early age.
Screening for Alzheimer’s Gene Tests the Desire to Know (Links to an external site)
The Hardest Test: Tucson family has hereditary Alzheimer’s (Links to an external site)
Dominantly Inherited Alzheimer’s Network-Trials Unit on PBS (Links to an external site)
Brian and Amelia Cottle’s story: Living with early onset Alzheimer’s disease (Links to an external site)
Dominantly Inherited Alzheimer Network Trial Completes Participant Enrollment for Two Drugs in Phase II/III Study of Amyloid Therapies (Links to an external site)
2015 Update
The Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) has completed the first stage of participant enrollment in the first Alzheimer’s prevention trial for autosomal dominant Alzheimer’s disease (ADAD), also referred to as early-onset Alzheimer’s disease. The goal of the first stage of the study is to determine the biomarker and cognitive effects of two different […]
34-year-old woman travels to Wash U for Alzheimer’s trial (Links to an external site)
A devastating disease that can rob you of your memory has an Alabama woman traveling to Missouri for help. The mother of three is taking part in a ground breaking study led by Washington University. Carrie Richardson, a 34-year-old preschool teacher and mother of three is in the fight of her life.
First trial to stop Alzheimer’s before symptoms emerge (Links to an external site)
Most research into dementia is about finding treatments for people who are already affected by symptoms. But a trial is under way in London which aims to prevent Alzheimer’s in people at high risk, before they show any physical signs of the disease.
Family with history of rare Alzheimer’s gene hopes for a cure (Links to an external site)
Can knowing you and your family may get Alzheimer’s ever be positive? (Links to an external site)
At the University of Washington’s School of Medicine there is a computer database that states with certainty – albeit heavily encrypted – whether or not Sophie Leggett will develop a form of genetically inherited early onset Alzheimer’s disease. But she has chosen not to find out what it says.
Slipping Away (Links to an external site)
Alzheimer’s: Experimental drug offers hope to families with legacy of degenerative brain disease (Links to an external site)
Alzheimer’s Association International Conference 2015: ADAD Family Conference (Links to an external site)
Families Affected by Early Alzheimer’s Seek Better Treatment (Links to an external site)
Younger Adults with Alzheimer’s are Key to Drug Research (Links to an external site)
Fast-Forwarding Treatment for Neurodegenerative Disorders (Links to an external site)
Researchers at the Leonard Wolfson Experimental Neurology Centre in London, UK, want to accelerate early-stage treatment trials for neurodegenerative disorders. Dara Mohammadi speaks to the investigators about the need to stimulate drug discovery.
Why a Woman in her 30s Decided to Find Out If She Will Get Alzheimer’s (Links to an external site)
Reason To Hope: Thank You (Video) (Links to an external site)
NHK Special: “Stop Alzheimer’s Disease!” won Takayanagi Prize (Links to an external site)
In a New Approach to Fighting Disease, Helpful Genetic Mutations Are Sought (Links to an external site)
