DIAN Observational Study Publications

  1. Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Buerger K, Levin J, Duering M, Dichgans M, Suárez-Calvet M, Haass C, Gordon BA, Lim YY, Masters CL, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Milz E, Moreno-Grau S, Teipel S, Grothe MJ, Kilimann I, Rossor M, Fox N, Laske C, Chhatwal J, Falkai P, Perneczky R, Lee JH, Spottke A, Boecker H, Brosseron F, Fliessbach K, Heneka MT, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero MÁ, Metzger C, Bittner D, Salloway S, Danek A, Hassenstab J, Yakushev I, Schofield PR, Morris JC, Bateman RJ, Ewers M. The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease. Mol Psychiatry. 2021 Feb;26(2):614-628. doi: 10.1038/s41380-019-0404-6. Epub 2019 Mar 21. PubMed PMID: 30899092; PubMed Central PMCID: PMC6754794.
  2. Chatterjee P, Fagan AM, Xiong C, McKay M, Bhatnagar A, Wu Y, Singh AK, Taddei K, Martins I, Gardener SL, Molloy MP, Multhaup G, Masters CL, Schofield PR, Benzinger TLS, Morris JC, Bateman RJ, Greenberg SM, Wermer MJH, van Buchem MA, Sohrabi HR, Martins RN. Presymptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy-Related Blood Metabolite Alterations. J Alzheimers Dis. 2021;79(2):895-903. doi: 10.3233/JAD-201267. PubMed PMID: 33361604.
  3. Luo J, Agboola F, Grant E, Masters CL, Albert MS, Johnson SC, McDade EM, Vöglein J, Fagan AM, Benzinger T, Massoumzadeh P, Hassenstab J, Bateman RJ, Morris JC, Perrin RJ, Chhatwal J, Jucker M, Ghetti B, Cruchaga C, Graff-Radford NR, Schofield PR, Mori H, Xiong C. Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study. Neurology. 2020 Dec 8;95(23):e3104-e3116. doi: 10.1212/WNL.0000000000010747. Epub 2020 Sep 1. PubMed PMID: 32873693; PubMed Central PMCID: PMC7734923.
  4. Montal V, Vilaplana E, Pegueroles J, Bejanin A, Alcolea D, Carmona-Iragui M, Clarimón J, Levin J, Cruchaga C, Graff-Radford NR, Noble JM, Lee JH, Allegri R, Karch CM, Laske C, Schofield PR, Salloway S, Ances B, Benzinger T, McDale E, Bateman R, Blesa R, Sánchez-Valle R, Lleó A, Fortea J. Biphasic cortical macro- and microstructural changes in autosomal dominant Alzheimer’s disease. Alzheimers Dement. 2020 Nov 16;. doi: 10.1002/alz.12224. [Epub ahead of print] PubMed PMID: 33196147.
  5. Chen CD, Holden TR, Gordon BA, Franklin EE, Li Y, Coble DW, Luo H, Bateman RJ, Ances BM, Perrin RJ, Benzinger TLS, Cairns NJ, Morris JC. Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer’s disease. Ann Clin Transl Neurol. 2020 Nov 5;. doi: 10.1002/acn3.51237. [Epub ahead of print] PubMed PMID: 33150749; PubMed Central PMCID: PMC7732239.
  6. Gonneaud J, Bedetti C, Pichet Binette A, Benzinger TLS, Morris JC, Bateman RJ, Poirier J, Breitner JCS, Villeneuve S. Association of education with Aβ burden in preclinical familial and sporadic Alzheimer disease. Neurology. 2020 Sep 15;95(11):e1554-e1564. doi: 10.1212/WNL.0000000000010314. Epub 2020 Aug 5. PubMed PMID: 32759192; PubMed Central PMCID: PMC7713743.
  7. Vermunt L, Dicks E, Wang G, Dincer A, Flores S, Keefe SJ, Berman SB, Cash DM, Chhatwal JP, Cruchaga C, Fox NC, Ghetti B, Graff-Radford NR, Hassenstab J, Karch CM, Laske C, Levin J, Masters CL, McDade E, Mori H, Morris JC, Noble JM, Perrin RJ, Schofield PR, Xiong C, Scheltens P, Visser PJ, Bateman RJ, Benzinger TLS, Tijms BM, Gordon BA. Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer’s disease. Brain Commun. 2020;2(2):fcaa102. doi: 10.1093/braincomms/fcaa102. eCollection 2020. PubMed PMID: 32954344; PubMed Central PMCID: PMC7475695.
  8. Hsu S, Pimenova AA, Hayes K, Villa JA, Rosene MJ, Jere M, Goate AM, Karch CM. Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2. Neurobiol Dis. 2020 Jun;139:104817. doi: 10.1016/j.nbd.2020.104817. Epub 2020 Feb 19. PubMed PMID: 32087291; PubMed Central PMCID: PMC7236786.
  9. Castillo-Barnes D, Su L, Ramírez J, Salas-Gonzalez D, Martinez-Murcia FJ, Illan IA, Segovia F, Ortiz A, Cruchaga C, Farlow MR, Xiong C, Graff-Radford NR, Schofield PR, Masters CL, Salloway S, Jucker M, Mori H, Levin J, Gorriz JM. Autosomal Dominantly Inherited Alzheimer Disease: Analysis of genetic subgroups by Machine Learning. Inf Fusion. 2020 Jun;58:153-167. doi: 10.1016/j.inffus.2020.01.001. Epub 2020 Jan 7. PubMed PMID: 32284705; PubMed Central PMCID: PMC7153760.
  10. Gordon BA. Neurofilaments in disease: what do we know?. Curr Opin Neurobiol. 2020 Apr;61:105-115. doi: 10.1016/j.conb.2020.02.001. Epub 2020 Mar 6. Review. PubMed PMID: 32151970; PubMed Central PMCID: PMC7198337.
  11. Barthélemy NR, Li Y, Joseph-Mathurin N, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Perrin RJ, Goate AM, Morris JC, Karch CM, Xiong C, Allegri R, Mendez PC, Berman SB, Ikeuchi T, Mori H, Shimada H, Shoji M, Suzuki K, Noble J, Farlow M, Chhatwal J, Graff-Radford NR, Salloway S, Schofield PR, Masters CL, Martins RN, O’Connor A, Fox NC, Levin J, Jucker M, Gabelle A, Lehmann S, Sato C, Bateman RJ, McDade E. A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease. Nat Med. 2020 Mar;26(3):398-407. doi: 10.1038/s41591-020-0781-z. Epub 2020 Mar 11. PubMed PMID: 32161412; PubMed Central PMCID: PMC7309367.
  12. Franzmeier N, Koutsouleris N, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Duering M, Dichgans M, Levin J, Gordon BA, Lim YY, Masters CL, Rossor M, Fox NC, O’Connor A, Chhatwal J, Salloway S, Danek A, Hassenstab J, Schofield PR, Morris JC, Bateman RJ, Ewers M. Predicting sporadic Alzheimer’s disease progression via inherited Alzheimer’s disease-informed machine-learning. Alzheimers Dement. 2020 Mar;16(3):501-511. doi: 10.1002/alz.12032. Epub 2020 Feb 11. PubMed PMID: 32043733; PubMed Central PMCID: PMC7222030.
  13. Pichet Binette A, Vachon-Presseau É, Morris J, Bateman R, Benzinger T, Collins DL, Poirier J, Breitner JCS, Villeneuve S. Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer’s Disease. Biol Psychiatry. 2020 Feb 6;. doi: 10.1016/j.biopsych.2020.01.023. [Epub ahead of print] PubMed PMID: 32228870; PubMed Central PMCID: PMC7415608.
  14. Day GS, Rappai T, Sathyan S, Morris JC. Deciphering the factors that influence participation in studies requiring serial lumbar punctures. Alzheimers Dement (Amst). 2020;12(1):e12003. doi: 10.1002/dad2.12003. eCollection 2020. PubMed PMID: 32211499; PubMed Central PMCID: PMC7085282.
  15. Aschenbrenner AJ, James BD, McDade E, Wang G, Lim YY, Benzinger TLS, Cruchaga C, Goate A, Xiong C, Perrin R, Buckles V, Allegri R, Berman SB, Chhatwal JP, Fagan A, Farlow M, O’Connor A, Ghetti B, Graff-Radford N, Goldman J, Gräber S, Karch CM, Lee JH, Levin J, Martins RN, Masters C, Mori H, Noble J, Salloway S, Schofield P, Morris JC, Bateman RJ, Hassenstab J. Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN). Alzheimers Dement. 2020 Jan;16(1):219-228. doi: 10.1002/alz.12010. PubMed PMID: 31914221; PubMed Central PMCID: PMC7206736.
  16. Ng KP, Richard-Devantoy S, Bertrand JA, Jiang L, Pascoal TA, Mathotaarachchi S, Therriault J, Yatawara C, Kandiah N, Greenwood CMT, Rosa-Neto P, Gauthier S. Suicidal ideation is common in autosomal dominant Alzheimer’s disease at-risk persons. Int J Geriatr Psychiatry. 2020 Jan;35(1):60-68. doi: 10.1002/gps.5215. Epub 2019 Oct 22. PubMed PMID: 31642105; PubMed Central PMCID: PMC7232741.
  17. Lessov-Schlaggar CN, Del Rosario OL, Morris JC, Ances BM, Schlaggar BL, Constantino JN. Adaptation of the Clinical Dementia Rating Scale for adults with Down syndrome. J Neurodev Disord. 2019 Dec 16;11(1):39. doi: 10.1186/s11689-019-9300-2. PubMed PMID: 31842726; PubMed Central PMCID: PMC6912998.
  18. Llibre-Guerra JJ, Li Y, Schindler SE, Gordon BA, Fagan AM, Morris JC, Benzinger TLS, Hassenstab J, Wang G, Allegri R, Berman SB, Chhatwal J, Farlow MR, Holtzman DM, Jucker M, Levin J, Noble JM, Salloway S, Schofield P, Karch C, Fox NC, Xiong C, Bateman RJ, McDade E. Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease. JAMA Netw Open. 2019 Dec 2;2(12):e1917126. doi: 10.1001/jamanetworkopen.2019.17126. PubMed PMID: 31825500; PubMed Central PMCID: PMC6991202.
  19. Maserejian N, Bian S, Wang W, Jaeger J, Syrjanen JA, Aakre J, Jack CR Jr, Mielke MM, Gao F. Practical algorithms for amyloid β probability in subjective or mild cognitive impairment. Alzheimers Dement (Amst). 2019 Dec;11:180. doi: 10.1016/j.dadm.2019.09.001. eCollection 2019 Dec. PubMed PMID: 31700988; PubMed Central PMCID: PMC6827360.
  20. Su Y, Flores S, Wang G, Hornbeck RC, Speidel B, Joseph-Mathurin N, Vlassenko AG, Gordon BA, Koeppe RA, Klunk WE, Jack CR Jr, Farlow MR, Salloway S, Snider BJ, Berman SB, Roberson ED, Brosch J, Jimenez-Velazques I, van Dyck CH, Galasko D, Yuan SH, Jayadev S, Honig LS, Gauthier S, Hsiung GR, Masellis M, Brooks WS, Fulham M, Clarnette R, Masters CL, Wallon D, Hannequin D, Dubois B, Pariente J, Sanchez-Valle R, Mummery C, Ringman JM, Bottlaender M, Klein G, Milosavljevic-Ristic S, McDade E, Xiong C, Morris JC, Bateman RJ, Benzinger TLS. Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies. Alzheimers Dement (Amst). 2019 Dec;11:180-190. doi: 10.1016/j.dadm.2018.12.008. eCollection 2019 Dec. PubMed PMID: 30847382; PubMed Central PMCID: PMC6389727.
  21. Gallagher M, Okonkwo OC, Resnick SM, Jagust WJ, Benzinger TLS, Rapp PR. What are the threats to successful brain and cognitive aging?. Neurobiol Aging. 2019 Nov;83:130-134. doi: 10.1016/j.neurobiolaging.2019.04.016. PubMed PMID: 31732016; PubMed Central PMCID: PMC6859944.
  22. Dube U, Del-Aguila JL, Li Z, Budde JP, Jiang S, Hsu S, Ibanez L, Fernandez MV, Farias F, Norton J, Gentsch J, Wang F, Salloway S, Masters CL, Lee JH, Graff-Radford NR, Chhatwal JP, Bateman RJ, Morris JC, Karch CM, Harari O, Cruchaga C. An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations. Nat Neurosci. 2019 Nov;22(11):1903-1912. doi: 10.1038/s41593-019-0501-5. Epub 2019 Oct 7. PubMed PMID: 31591557; PubMed Central PMCID: PMC6858549.
  23. Xiong C, Luo J, Agboola F, Li Y, Albert M, Johnson SC, Koscik RL, Masters CL, Soldan A, Villemagne VL, Li QX, McDade EM, Fagan AM, Massoumzadeh P, Benzinger T, Hassenstab J, Bateman RJ, Morris JC. A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer’s disease from young adulthood and for designing prevention trials. Alzheimers Dement. 2019 Nov;15(11):1448-1457. doi: 10.1016/j.jalz.2019.06.4955. Epub 2019 Sep 7. PubMed PMID: 31506247; PubMed Central PMCID: PMC6874758.
  24. Carpenter CR, McFarland F, Avidan M, Berger M, Inouye SK, Karlawish J, Lin FR, Marcantonio E, Morris JC, Reuben DB, Shah RC, Whitson HE, Asthana S, Verghese J. Impact of Cognitive Impairment Across Specialties: Summary of a Report From the U13 Conference Series. J Am Geriatr Soc. 2019 Oct;67(10):2011-2017. doi: 10.1111/jgs.16093. Epub 2019 Aug 22. PubMed PMID: 31436318; PubMed Central PMCID: PMC6800784.
  25. Schultz AP, Kloet RW, Sohrabi HR, van der Weerd L, van Rooden S, Wermer MJH, Moursel LG, Yaqub M, van Berckel BNM, Chatterjee P, Gardener SL, Taddei K, Fagan AM, Benzinger TL, Morris JC, Sperling R, Johnson K, Bateman RJ, Gurol ME, van Buchem MA, Martins R, Chhatwal JP, Greenberg SM. Amyloid imaging of dutch-type hereditary cerebral amyloid angiopathy carriers. Ann Neurol. 2019 Oct;86(4):616-625. doi: 10.1002/ana.25560. Epub 2019 Aug 12. PubMed PMID: 31361916; PubMed Central PMCID: PMC6876775.
  26. Deming Y, Filipello F, Cignarella F, Cantoni C, Hsu S, Mikesell R, Li Z, Del-Aguila JL, Dube U, Farias FG, Bradley J, Budde J, Ibanez L, Fernandez MV, Blennow K, Zetterberg H, Heslegrave A, Johansson PM, Svensson J, Nellgård B, Lleo A, Alcolea D, Clarimon J, Rami L, Molinuevo JL, Suárez-Calvet M, Morenas-Rodríguez E, Kleinberger G, Ewers M, Harari O, Haass C, Brett TJ, Benitez BA, Karch CM, Piccio L, Cruchaga C. The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk. Sci Transl Med. 2019 Aug 14;11(505). doi: 10.1126/scitranslmed.aau2291. PubMed PMID: 31413141; PubMed Central PMCID: PMC6697053.
  27. Navid J, Day GS, Strain J, Perrin RJ, Bucelli RC, Dincer A, Wisch JK, Soleimani-Meigooni D, Morris JC, Benzinger TLS, Ances BM. Structural signature of sporadic Creutzfeldt-Jakob disease. Eur J Neurol. 2019 Aug;26(8):1037-1043. doi: 10.1111/ene.13930. Epub 2019 Mar 25. PubMed PMID: 30735286; PubMed Central PMCID: PMC6615963.
  28. Buckley RF, Mormino EC, Chhatwal J, Schultz AP, Rabin JS, Rentz DM, Acar D, Properzi MJ, Dumurgier J, Jacobs H, Gomez-Isla T, Johnson KA, Sperling RA, Hanseeuw BJ. Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid. Neurobiol Aging. 2019 Jun;78:178-185. doi: 10.1016/j.neurobiolaging.2019.02.019. Epub 2019 Mar 7. PubMed PMID: 30947113; PubMed Central PMCID: PMC6545139.
  29. Vöglein J, Paumier K, Jucker M, Preische O, McDade E, Hassenstab J, Benzinger TL, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal J, Salloway S, Xiong C, Karch CM, Cairns N, Mori H, Schofield PR, Masters CL, Goate A, Buckles V, Fox N, Rossor M, Chrem P, Allegri R, Ringman JM, Höglinger G, Steiner H, Dieterich M, Haass C, Laske C, Morris JC, Bateman RJ, Danek A, Levin J. Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer’s disease. Brain. 2019 May 1;142(5):1429-1440. doi: 10.1093/brain/awz050. PubMed PMID: 30897203; PubMed Central PMCID: PMC6735903.
  30. Schindler SE, Li Y, Todd KW, Herries EM, Henson RL, Gray JD, Wang G, Graham DL, Shaw LM, Trojanowski JQ, Hassenstab JJ, Benzinger TLS, Cruchaga C, Jucker M, Levin J, Chhatwal JP, Noble JM, Ringman JM, Graff-Radford NR, Holtzman DM, Ladenson JH, Morris JC, Bateman RJ, Xiong C, Fagan AM. Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer’s disease. Alzheimers Dement. 2019 May;15(5):655-665. doi: 10.1016/j.jalz.2018.12.019. Epub 2019 Mar 4. PubMed PMID: 30846386; PubMed Central PMCID: PMC6511459.
  31. Gordon BA, Blazey TM, Christensen J, Dincer A, Flores S, Keefe S, Chen C, Su Y, McDade EM, Wang G, Li Y, Hassenstab J, Aschenbrenner A, Hornbeck R, Jack CR, Ances BM, Berman SB, Brosch JR, Galasko D, Gauthier S, Lah JJ, Masellis M, van Dyck CH, Mintun MA, Klein G, Ristic S, Cairns NJ, Marcus DS, Xiong C, Holtzman DM, Raichle ME, Morris JC, Bateman RJ, Benzinger TLS. Tau PET in autosomal dominant Alzheimer’s disease: relationship with cognition, dementia and other biomarkers. Brain. 2019 Apr 1;142(4):1063-1076. doi: 10.1093/brain/awz019. PubMed PMID: 30753379; PubMed Central PMCID: PMC6439328.
  32. Han JY, Besser LM, Xiong C, Kukull WA, Morris JC. Cholinesterase Inhibitors May Not Benefit Mild Cognitive Impairment and Mild Alzheimer Disease Dementia. Alzheimer Dis Assoc Disord. 2019 Apr-Jun;33(2):87-94. doi: 10.1097/WAD.0000000000000291. PubMed PMID: 30633043; PubMed Central PMCID: PMC6542289.
  33. Wang G, Coble D, McDade EM, Hassenstab J, Fagan AM, Benzinger TLS, Bateman RJ, Morris JC, Xiong C. Staging biomarkers in preclinical autosomal dominant Alzheimer’s disease by estimated years to symptom onset. Alzheimers Dement. 2019 Apr;15(4):506-514. doi: 10.1016/j.jalz.2018.12.008. Epub 2019 Feb 15. PubMed PMID: 30773445; PubMed Central PMCID: PMC6461496.
  34. Vöglein J, Noachtar S, McDade E, Quaid KA, Salloway S, Ghetti B, Noble J, Berman S, Chhatwal J, Mori H, Fox N, Allegri R, Masters CL, Buckles V, Ringman JM, Rossor M, Schofield PR, Sperling R, Jucker M, Laske C, Paumier K, Morris JC, Bateman RJ, Levin J, Danek A. Seizures as an early symptom of autosomal dominant Alzheimer’s disease. Neurobiol Aging. 2019 Apr;76:18-23. doi: 10.1016/j.neurobiolaging.2018.11.022. Epub 2018 Dec 5. PubMed PMID: 30616208; PubMed Central PMCID: PMC6572755.
  35. Wang Q, Wang Y, Liu J, Sutphen CL, Cruchaga C, Blazey T, Gordon BA, Su Y, Chen C, Shimony JS, Ances BM, Cairns NJ, Fagan AM, Morris JC, Benzinger TLS. Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer’s disease. Neuroimage Clin. 2019;22:101767. doi: 10.1016/j.nicl.2019.101767. Epub 2019 Mar 13. PubMed PMID: 30901713; PubMed Central PMCID: PMC6428957.
  36. Bussy A, Snider BJ, Coble D, Xiong C, Fagan AM, Cruchaga C, Benzinger TLS, Gordon BA, Hassenstab J, Bateman RJ, Morris JC. Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network. Neurobiol Aging. 2019 Mar;75:42-50. doi: 10.1016/j.neurobiolaging.2018.10.011. Epub 2018 Oct 13. PubMed PMID: 30530186; PubMed Central PMCID: PMC6385602.
  37. Preische O, Schultz SA, Apel A, Kuhle J, Kaeser SA, Barro C, Gräber S, Kuder-Buletta E, LaFougere C, Laske C, Vöglein J, Levin J, Masters CL, Martins R, Schofield PR, Rossor MN, Graff-Radford NR, Salloway S, Ghetti B, Ringman JM, Noble JM, Chhatwal J, Goate AM, Benzinger TLS, Morris JC, Bateman RJ, Wang G, Fagan AM, McDade EM, Gordon BA, Jucker M. Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease. Nat Med. 2019 Feb;25(2):277-283. doi: 10.1038/s41591-018-0304-3. Epub 2019 Jan 21. PubMed PMID: 30664784; PubMed Central PMCID: PMC6367005.
  38. Properzi MJ, Buckley RF, Chhatwal JP, Donohue MC, Lois C, Mormino EC, Johnson KA, Sperling RA, Schultz AP. Nonlinear Distributional Mapping (NoDiM) for harmonization across amyloid-PET radiotracers. Neuroimage. 2019 Feb 1;186:446-454. doi: 10.1016/j.neuroimage.2018.11.019. Epub 2018 Nov 17. PubMed PMID: 30458305; PubMed Central PMCID: PMC6338495.
  39. Toedebusch CD, McLeland JS, Schaibley CM, Banks IR, Boyd J, Morris JC, Holtzman DM, Lucey BP. Multi-Modal Home Sleep Monitoring in Older Adults. J Vis Exp. 2019 Jan 26;(143). doi: 10.3791/58823. PubMed PMID: 30741255; PubMed Central PMCID: PMC6377867.
  40. Day GS, Gordon BA, Perrin RJ, Ances BM. Author response: In vivo [18F]-AV-1451 tau-PET imaging in sporadic Creutzfeldt-Jakob disease. Neurology. 2019 Jan 15;92(3):150. doi: 10.1212/WNL.0000000000006771. PubMed PMID: 30643031.
  42. Lucey BP, McCullough A, Landsness EC, Toedebusch CD, McLeland JS, Zaza AM, Fagan AM, McCue L, Xiong C, Morris JC, Benzinger TLS, Holtzman DM. Reduced non-rapid eye movement sleep is associated with tau pathology in early Alzheimer’s disease. Sci Transl Med. 2019 Jan 9;11(474). doi: 10.1126/scitranslmed.aau6550. PubMed PMID: 30626715; PubMed Central PMCID: PMC6342564.
  43. Roe CM, Stout SH, Rajasekar G, Ances BM, Jones JM, Head D, Benzinger TLS, Williams MM, Davis JD, Ott BR, Warren DK, Babulal GM. A 2.5-Year Longitudinal Assessment of Naturalistic Driving in Preclinical Alzheimer’s Disease. J Alzheimers Dis. 2019;68(4):1625-1633. doi: 10.3233/JAD-181242. PubMed PMID: 30958365; PubMed Central PMCID: PMC6488385.
  44. Barroeta-Espar I, Weinstock LD, Perez-Nievas BG, Meltzer AC, Siao Tick Chong M, Amaral AC, Murray ME, Moulder KL, Morris JC, Cairns NJ, Parisi JE, Lowe VJ, Petersen RC, Kofler J, Ikonomovic MD, López O, Klunk WE, Mayeux RP, Frosch MP, Wood LB, Gomez-Isla T. Distinct cytokine profiles in human brains resilient to Alzheimer’s pathology. Neurobiol Dis. 2019 Jan;121:327-337. doi: 10.1016/j.nbd.2018.10.009. Epub 2018 Oct 15. PubMed PMID: 30336198; PubMed Central PMCID: PMC6437670.
  45. Veitch DP, Weiner MW, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR Jr, Jagust W, Morris JC, Petersen RC, Saykin AJ, Shaw LM, Toga AW, Trojanowski JQ. Understanding disease progression and improving Alzheimer’s disease clinical trials: Recent highlights from the Alzheimer’s Disease Neuroimaging Initiative. Alzheimers Dement. 2019 Jan;15(1):106-152. doi: 10.1016/j.jalz.2018.08.005. Epub 2018 Oct 13. Review. PubMed PMID: 30321505.
  46. Jiang S, Wen N, Li Z, Dube U, Del Aguila J, Budde J, Martinez R, Hsu S, Fernandez MV, Cairns NJ, Harari O, Cruchaga C, Karch CM. Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP. Transl Psychiatry. 2018 Dec 13;8(1):265. doi: 10.1038/s41398-018-0319-z. PubMed PMID: 30546007; PubMed Central PMCID: PMC6293323.
  47. Wang G, Xiong C, McDade EM, Hassenstab J, Aschenbrenner AJ, Fagan AM, Benzinger TLS, Gordon BA, Morris JC, Li Y, Bateman RJ. Simultaneously evaluating the effect of baseline levels and longitudinal changes in disease biomarkers on cognition in dominantly inherited Alzheimer’s disease. Alzheimers Dement (N Y). 2018;4:669-676. doi: 10.1016/j.trci.2018.10.009. eCollection 2018. PubMed PMID: 30569014; PubMed Central PMCID: PMC6288312.
  48. Suárez-Calvet M, Capell A, Araque Caballero MÁ, Morenas-Rodríguez E, Fellerer K, Franzmeier N, Kleinberger G, Eren E, Deming Y, Piccio L, Karch CM, Cruchaga C, Paumier K, Bateman RJ, Fagan AM, Morris JC, Levin J, Danek A, Jucker M, Masters CL, Rossor MN, Ringman JM, Shaw LM, Trojanowski JQ, Weiner M, Ewers M, Haass C. CSF progranulin increases in the course of Alzheimer’s disease and is associated with sTREM2, neurodegeneration and cognitive decline. EMBO Mol Med. 2018 Dec;10(12). doi: 10.15252/emmm.201809712. PubMed PMID: 30482868; PubMed Central PMCID: PMC6284390.
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  63. Vlassenko AG, Gordon BA, Goyal MS, Su Y, Blazey TM, Durbin TJ, Couture LE, Christensen JJ, Jafri H, Morris JC, Raichle ME, Benzinger TL. Aerobic glycolysis and tau deposition in preclinical Alzheimer’s disease. Neurobiol Aging. 2018 Jul;67:95-98. doi: 10.1016/j.neurobiolaging.2018.03.014. Epub 2018 Mar 20. PubMed PMID: 29655050; PubMed Central PMCID: PMC5955846.
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