Preventing Alzheimer’s (Links to an external site)
Finding ways to diagnose and treat this devastating disease has frustrated scientists and clinicians ever since. Now the long and hard-fought campaign against Alzheimer’s has reached a potentially significant milestone: the launch of the first clinical trials to test whether new drug treatments given before dementia can prevent the disease.
Multicompany trials adapt to disciplines beyond cancer (Links to an external site)
Trials at Washington U. medical school offer hope for Alzheimer’s treatment (Links to an external site)
Unraveling Alzheimer’s mysteries in search of new treatment (Links to an external site)
Over the past several decades scientists have begun to unravel the complicated process that leads to the death of brain cells and, ultimately, the disease we call Alzheimer’s. That new understanding may lead to therapies that can halt the disease before symptoms appear and brains are irreparably damaged.
In Familial AD, Aß Production Up, Clearance Down (Links to an external site)
Researchers have long assumed that people with familial Alzheimer’s disease make too much Aβ42 in the brain, but they lacked proof. Now, in the June 12 Science Translational Medicine, researchers led by Randall Bateman at Washington University in St. Louis, Missouri, provide the first direct evidence.
Innovations: Alzheimer’s Disease: New Hope in Scientific Studies (Links to an external site)
Could there possibly be a cure for Alzheimer’s disease in the future? Through the current DIAN Network Study and Drug Trials headquartered at Washington University in St. Louis, early detection and prevention could become a reality. Dr. Randall Bateman, Charles F. and Joanne Knight Distinguished Professor in Neurology Washington University School of Medicine in St. […]
Study to find possible Alzheimer’s breakthrough (Links to an external site)
The urgent need for better treatment of Alzheimer ‘s disease and other kinds of dementia was highlighted this past week with a report that said dementia cost this country as much as $215 billion a year. well, now there is a fascinating study going on involving some new drugs that might prevent Alzheimer ‘s. we […]
Washington University Researchers Hope Drug Cures Alzheimer’s Disease (Links to an external site)
Very few people carry that mutation, but enough have it for Washington University researchers to test three drugs that could offer hope for them, and the larger search for a cure.
Investigational drugs chosen for major Alzheimer’s prevention trial (Links to an external site)
Stopping Alzheimer’s Before It Starts (Links to an external site)
Three new clinical trials expected to begin next year will attempt to prevent dementia by treating people at risk for the disease before they develop symptoms.
Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease (Links to an external site)
Randall J. Bateman, M.D., Chengjie Xiong, Ph.D.,Tammie L.S. Benzinger, M.D., Ph.D., Anne M. Fagan, Ph.D.,Alison Goate, Ph.D., Nick C. Fox, M.D., Daniel S. Marcus, Ph.D.,Nigel J. Cairns, Ph.D., Xianyun Xie, M.S., Tyler M. Blazey, B.S.,David M. Holtzman, M.D., Anna Santacruz, B.S., Virginia Buckles, Ph.D.,Angela Oliver, R.N., Krista Moulder, Ph.D., Paul S. Aisen, M.D.,Bernardino Ghetti, M.D., […]
First detailed timeline established for brain’s descent into Alzheimer’s (Links to an external site)
Scientists have assembled the most detailed chronology to date of the human brain’s long, slow slide into full-blown Alzheimer’s disease.