DIAN Observational Study Related Entities

Subcontractors

Washington University in St. Louis has contracted with the following investigators and institutions to assist in the conduct of the project research:

  • Alzheimer’s Disease Cooperative Study (ADCS): Howard Feldman, MD—coordination of clinical and neuropsychological evaluations and monitoring of the acquisition of imaging studies and collection of biological fluids.
  • Mayo Clinic, Rochester, MN: Clifford Jack, MD, PhD—MRI site training and standardization.
  • University of Michigan: Robert Koeppe, PhD—PET site training and standardization.

Steering committee

A steering committee composed of DIAN’s principal investigators, associate directors, executive director, core leaders, performance site leaders, principal investigators from ADNI and the ADCS, a bioethicist, autosomal dominant Alzheimer’s disease family representatives, representatives of the Food and Drug Administration, and appropriate staff from the National Institute of Aging will govern the research.

Washington University

(DIAN Coordinating Center; Performance Site)

  • Randall Bateman (site PI), Director & Principal Investigator
  • John C. Morris, Associate Director & Clinical Core Leader
  • David M. Holtzman, Associate Director
  • Alison M. Goate, Associate Director & Genetics Core Leader
  • Carlos Cruchaga, Genetics Core Co-Leader
  • Katrina Paumier, Deputy Director
  • Chengjie Xiong, Biostatistics Core Leader
  • Nigel J. Cairns, Neuropathology Core Leader
  • Anne M. Fagan, Biomarker Core Leader
  • Tammie Benzinger, Imaging Core Leader
  • Dan Marcus, Informatics Core Leader

Argentina site

  • Ricardo Allegri (Site PI), Fleni

Australia sites

  • Peter Schofield (Site PI), Neuroscience Research Australia, Sydney
  • Ralph Martins (Site PI), Edith Cowan University, Perth
  • Colin Masters (Site PI), University of Melbourne

German sites

  • Mathias Jucker (Site PI), University of Tübingen
  • Johannes Levin (Site PI), University of Munich

Japan sites

  • Hiroshi Mori, Japan Consortium PI

Korea site

  • Jae-Hong Lee (Site PI), Asan Medical Center

United Kingdom site

  • Martin Rossor (Site PI), University College, London/Institute of Neurology

United States sites

  • Jasmeer Chhatwal (Site PI), Massachusetts General Hospital/Brigham and Women’s Hospital
  • Stephen Salloway (Site PI), Butler Hospital/Brown University
  • James Noble (Site PI), Columbia University
  • Bernardino Ghetti (Site PI), Indiana University
  • Helen Chui (Site PI), University of Southern California
  • Sarah Berman (Site PI), University of Pittsburgh
  • Neill Graff-Radford (Site PI), Mayo Clinic Jacksonville

Other steering committee members

  • Michael W. Weiner, Alzheimer’s Disease Neuroimaging Initiative
  • Kimberly Quaid, Indiana University Center for Bioethics
  • Neil Buckholtz, John K. Hsiao and Laurie Ryan, National Institute on Aging
  • Two members of families with dominantly inherited Alzheimer’s disease

External Advisory Committee

Members of the External Advisory Committee (EAC) will review DIAN annually to evaluate progress, assess the effectiveness of communication among the grant components, and ensure that the conduct of the sites is of the highest possible quality. Current EAC members are:

  • Eric Reiman, Banner Health, Arizona, Chair
  • Thomas Montine, Stanford University
  • Michael Hutton, Eli Lilly,
  • Peter St George-Hyslop, University of Cambridge, by phone and webinar
  • Karen Bandeen-Roche, John Hopkins University
  • Kathleen Welsh-Bohmer, Duke University
  • Roger Rosenberg, University of Texas Southwestern