Investigator:Jason Hassenstab
Title:Optimizing Cognitive Assessment in DIAN with Smartphone-Based Burst Testing
Date of Request:11/22/2019
Aim 1:Determine if ARC burst assessments will better characterize the nature and magnitude of cognitive decline in DIAD mutation carriers than traditional in-clinic cognitive assessments
Aim 2:Compare cross-sectional and longitudinal associations between ARC assessments and neuroimaging and fluid biomarkers in DIAD
Aim 3:Examine the role of environment, mood, fatigue, and sleep patterns on cognition in DIAD