Investigator:Brian Gordon
Title:Comparing biomarkers between Down Syndrome, Autosomal Dominant, and Late onset Alzheimer Disease
Date of Request:03/25/2022
Status:approved
ID:DIAN-D2208
Aim 1:How do measures of tau pathology measured using PET compare among DS, ADAD, and LOAD?
Aim 2:Does the spread of tau pathology over time differ between cohorts?
Aim 3:Are white matter lesions a common finding in all three forms of AD?
Aim 4How do biofluid profiles compare between DS, ADAD, and LOAD?